Follow I-35 South beyond Highway 90. After passing the Military Drive exit and the Zarzamora exit, take the Texas Hwy 16 (Poteet) exit on the right hand side. After you exit, stay on the access road until you come to the light at Hwy 16. Make a left onto Highway 16. Turn left at the fifth (5th) stop light onto Villaret Blvd. Campus entrance will be on your right.
From West Side:
Follow I-410 East to I-410 South. Exit at Texas Hwy 16. Turn left and go under I-410. Turn right at first stop light, which is Villaret Blvd. Campus entrance will be on your right.
From East Side:
Follow I-410 West to I-410 South. Exit at Texas Hwy16. On access road, before you reach Hwy 16, you will see on your right an entrance with a Palo Alto College sign. As you enter, the Performing Arts Center is in front of you, the main campus is on your right, and the Natatorium/Gymnasium Complex is on your left. The large building in the center of the campus is the Ozuna Learning Resources and Academic Computing Center.